Find a picture that you think has some good colours/tones and using the colour picker tool, start picking some colours out of it. This is also a good website http://colorschemedesigner.com/ if you want to create colour schemes.
picking colors from image is really nice idea, even that didnt come to my mind. Thank you.
Aether-Themes saidI didnt know that, yeah i use photoshop. Its a shame i am using it from past 11 years but never knew about kuler in photoshop. I am newbie to designing.
You can also get Adobe Kuler as an extension for PS (assuming you use PS for designing) – http://www.adobe.com/bg/products/kuler.html